Correlation of Antemortem Serum Creatine Kinase, Creatine Kinase-MB, Troponin I, and Troponin T with Cardiac Pathology

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Correlation of antemortem serum creatine kinase, creatine kinase-MB, troponin I, and troponin T with cardiac pathology.

BACKGROUND Spurious increases in serum troponins, especially troponin T, have been reported in patients with and without acute myocardial syndromes. METHODS We studied 78 autopsied patients without clinical myocardial infarction (MI) and correlated histologic cardiac findings with antemortem serum creatine kinase (CK), its MB isoenzyme (CK-MB), cardiac troponin I (cTnI), and cardiac troponin ...

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The mass concentrations of serum troponin T and creatine kinase-MB are elevated before creatine kinase and creatine kinase-MB activities in acute myocardial infarction.

The time-related frequency of elevated results for the mass concentrations of the MB isoenzyme of creatine kinase and of troponin T were compared with that of creatine kinase and creatine kinase-MB activity in patients with acute myocardial infarction. Patients (322; 175 with and 147 without myocardial infarction) consecutively admitted for evaluation of possible acute myocardial infarction wer...

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Cardiac troponin I, cardiac troponin T, and creatine kinase MB in dialysis patients without ischemic heart disease: evidence of cardiac troponin T expression in skeletal muscle.

Serum cardiac troponin T (cTnT) concentrations are frequently increased in chronic dialysis patients as measured by the first-generation ELISA immunoassay, as is creatine kinase (CK) MB mass in the absence of acute ischemic heart disease. We designed this study to compare four serum markers of myocardial injury [CK-MB mass, first-generation ELISA cTnT, second-generation Enzymun cTnT, and cardia...

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A comparison of cardiac troponin T and creatine kinase-MB for patient evaluation after cardiac surgery.

OBJECTIVES The aim of this study was to assess the role of serum markers of myocardial necrosis after cardiac surgery. BACKGROUND The role of serum troponin T (TnT) and creatine kinase-MB (CK-MB) for the risk stratification of patients after cardiac surgery remains undefined. METHODS Serum levels of TnT and CK-MB were measured from 224 patients every 8 h after cardiac surgery. The results o...

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Troponin I, troponin T, and creatine kinase-MB mass in patients with the carcinoid syndrome with and without heart failure.

all clinical diagnostic laboratories in the US failed to recognize these falsepositive ketone reactions in survey specimens (10 ). It is also relevant to mention that above-therapeutic concentrations of mesna, which carry a high reducing capacity, did not cause interference in two Chemstrip 10UA tests that are based on oxidation reactions (glucose by glucose oxidase/peroxidase and hemoglobin wi...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2000

ISSN: 0009-9147,1530-8561

DOI: 10.1093/clinchem/46.3.338